开始:VCALENDAR版本:2.0 PRODID: - / /乔迪实验室E乐动体育登录CPv5.1.0 / / NONSGML v1.0 / / EN CALSCALE:公历方法:发布X-WR-CALNAME:乔迪实验室X-ORIGINAL-URL: //www.buyjuzo.com X-WR-CALDESC:乔迪实验室开始的事件:VTIMEZONE TZID:美国/ New_York开始:日光TZOFFSETFROM: -0500 TZOFFSETTO: -0400 TZNAME: DTSTART美国东部时间:20210314 t070000结束:日光开始:标准TZOFFSETFROM: -0400 TZOFFSETTO: -0500 TZNAME:美国东部时间DTSTART: 20211107 t060000结束:标准结束:VTIMEZONE开始:VEVENT DTSTART; TZID =美国/ New_York: 20210715 t110000 DTEND; TZID =美国/ New_York: 20210715 t120000 DTSTAMP: 20220122 t120322创建:20210517 t202839z last - modified: 20210517 t203455z UID: 57296 - 1626346800 - 1626346800 @www.buyjuzo.com在本次网络研讨会中，我们将讨论基于多检测器的网络研讨会。刘伟西将展示“在E&L分析中减少响应因子(RF)变化的多检测器策略”。根据ISO 10993和<1664>的化学表征已成为医疗器械和药品测试的重要组成部分。关于可提取物和可浸出物研究的准确性的一个主要问题是由于响应因子(RF)变化造成的定量误差。最近的出版物强调了射频变异对两种LCMS构成的风险(Jordi等。医药和生物医学分析杂志150(2018)368-376)和GCMS (Jenke和Odufu, Journal of chromatography Science 2012; 50:206-212)。FDA已经认识到这个问题的重要性，因此在分析评价阈值(AET)的计算中增加了不确定因素(UF)。在本介绍中，使用多检测器策略的另一种定量策略，包括液相色谱质谱(LCMS)系统， ultraviolet (UV) and charged aerosol detection (CAD) as well as a Gas Chromatography system using mass spectroscopy (MS) and Flame Ionization Detection (FID) will be presented. Data comparing the response factors for more than 200 extractables will be presented demonstrating an approach to reduce overall RF variation. This reduced the associated need for UFs and increases confidence in the resulting risk assessments. \n\n\n\nKey Learning Objectives: \n\n\n\nLearn how the Multidetector Strategy addresses the problem of underreporting at the Analytical Evaluation Threshold (AET)Understand why the Multidetector Strategy provides for improved quantitative accuracyUnderstand the advantages and limitations of Response Factor (RF) databases\n\n\n\n\n\n\n\n\n\n\n\n\n URL://www.buyjuzo.com/event/webinar-the-multidetector-approach/ CATEGORIES:Extractables, Leachables and Elemental Impurities ATTACH;FMTTYPE=image/png://www.buyjuzo.com/wp-content/uploads/2021/05/image-47.png END:VEVENT END:VCALENDAR